"The elasticity of the cell cytoskeleton : some experiments with optical tweezers"

Sylvie Hénon

Laboratoire de Biorheology et d'Hydrodynamique Physico-chimique
Universités de Paris 6 et 7. Paris, France

Abstract

The mechanical behavior of living cells is mostly determined by its cytoskeleton, a complex structure of proteins, which play a determinant role in the shape and motility of the cells. The mechanical properties of some living cells were assessed with optical tweezers, a technique that allows the manipulation of small dielectric objects, such as micron-sized beads. The beads serve as handles to apply a controlled stress to the cell. I will present results obtained on a simple biological system (the membrane of the red blood cell and its skeleton), and on a more complex one (pulmonary epithelial cells in culture).
Elizabeth K. Mann